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These strategies have succeeded for small-molecule drugs and a limited number of short peptide fragments

Increased Susceptibility to Oxidant Injury in Hepatocytes From Rats With Intra-Abdominal Hypertension

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The cellular homeostasis between the GSH and GSSG ratio controls the cells redox level, maintained by reactions performed by glutathione reductases (GR) and glutathione peroxidases (GPX) (Mahmood et al., 2010)

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