Men with uncontrolled diabetes, insulin resistance, or metabolic disease should be evaluated carefully before starting peptides, since some peptides may affect appetite, blood sugar, insulin sensitivity, or fluid balance
Dietary interventions in fibromyalgia: a systematic review
Supporting Evidence A few studies focus on ipamorelins influence on GH
368, no
Unlike earlier secretagogues that stimulate multiple endocrine axes, ipamorelin shows constrained lactotroph activation
What to track Symptoms log: Hot flash frequency and severity Sleep quality (hours, quality 1-10) Energy levels daily Mood and anxiety Brain fog incidents Period timing (if still menstruating) Body composition: Weight weekly (understanding fluctuations normal) Body measurements (waist, hips) Photos every 2-4 weeks How clothes fit Muscle vs fat changes Hormone-related: Menstrual cycle length and flow PMS symptoms Breast tenderness Libido changes Vaginal dryness Quality of life: Exercise performance Work productivity Relationship satisfaction Social engagement Overall well-being Bloodwork for perimenopause peptides Baseline testing: Estradiol (estrogen) Progesterone Testosterone (total and free) FSH (follicle-stimulating hormone - elevated in perimenopause) Thyroid panel (TSH, Free T3, Free T4) IGF-1 (growth hormone marker) Fasting glucose and insulin Lipid panel Follow-up (every 3-6 months): IGF-1 (should increase with GH peptides) Thyroid panel Fasting glucose Hormones if on HRT Adjusting based on results: Low IGF-1 still
