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This observation leads to the question of whether supraphysiological stimulation (as occurs with GLP-1RA use) could accelerate the progression of PanIN lesions into PDAC

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(v) For CY 2014 through CY 2018, the Consumer Price Index for All Urban Consumers update determined under paragraph (a)(2)(ii) of this section was reduced by 2.0 percentage points for ASCs that failed to meet the standards for reporting of ASC quality measures as established by the Secretary for the corresponding calendar year

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