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Generic drugs provide additional treatment options which are generally more affordable for patients

Nutrition and Metabolism Volume 9 - 2022 | Abstract Depression has become one of the most common mental diseases in the world, but the understanding of its pathogenesis, diagnosis and treatments remains insufficient

The primary risks include increased hypoglycemia risk (especially with insulin or sulfonylureas), additive gastrointestinal symptoms such as nausea and diarrhea, and unknown effects on medication absorption due to tirzepatide's delayed gastric emptying

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(Bethesda, MD: ClinicalTrials.gov) (2025)

Because of this and the fact that patients dont gain weight while on the medication, sitagliptin has become more popular as a second-line treatment for those with type 2 diabetes (Bennett RG, 2018)