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10.1038/nature25486 Nature 267 Wong-RileyM
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The critical distinction: GLP-1 agonists modulate metabolism and hormonal signaling
For the four samples, the severity of the subcutaneous tissue necrosis and inflammatory cell infiltration was assessed by a trained toxicopathologist using a light microscope and scored on a numerical scale, where code 1 reflects no abnormality detected and code 5 reflects marked severity: 1 , no abnormality detected 2, minimal severity 3, mild severity 4, moderate severity 5, marked severity The co-formulation vehicles were evaluated for the level of subcutaneous tissue necrosis and inflammatory cell infiltration that they elicited upon subcutaneous injection
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