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Medication is a powerful tool to quiet the physical urge to use, but it is not a standalone cure for addiction

Neuropharmacology 150:145152 Martins IJ (2014) The global obesity epidemic is related to stroke, dementia and Alzheimers disease

These figures are, of course, on the upper end of the scale, and the weight reduction might be more or less

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Serum adiponectin and resistin in relation to insulin resistance and markers of hyperandrogenism in lean and obese women with polycystic ovary syndrome