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FOXO4-DRI's well-characterized mechanism and expanding research applications position it as an essential research tool for advancing our understanding of senescence biology and developing next-generation approaches to studying aging and age-related diseases in laboratory settings
There were 162 differentially expressed genes (DEGs) at 3 months and only 54 DEGs at 8 months in iSPN + mut compared with iSPN + wt (Fig
Average weight loss ranges from 1015% of body weight at the 1.7 mg dose to 1522% at the 2.4 mg maintenance dose over one year, depending on diet, exercise, and individual metabolism
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