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DOI Westmoreland C, Bender HJ, Doe JE, et al

Despite these advances, current available anti-obesity medications still face several challenges, including interindividual variability in treatment responses, side effects, and unintended loss of lean mass along with fat reduction

These studies varied widely in how they delivered dietary advice and measured nutrition outcomes, and they often lacked standardized methods and reporting

This endpoint is complex because it is difficult to achieve in clinical practice, and longterm adherence to lifestyle interventions is questionable [5]

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