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Lipo C is contraindicated in patients with Lebers hereditary optic neuropathy (cyanocobalamin can worsen this condition), active B12-dependent malignancies, severe kidney disease (impaired methionine clearance), or known hypersensitivity to any component

An integrated and unifying hypothesis for the metabolic basis of sporadic Alzheimers disease

Regul Pept 2(2):139150

Abstract Despite advances in immunotherapy, triple-negative breast cancer (TNBC) remains a major therapeutic challenge owing to its marked aggressiveness, low immunogenicity, and limited responsiveness to immune checkpoint blockade (ICB)

Remission occurred in 20.3%, and 18.6% of patients needed to discontinue TNF alpha inhibitor therapy

Diabetes and Glucose Metabolism Studies Studies indicate that diabetes research focusing on glucose uptake in muscle and fat tissues represents an emerging application area