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[DOI] [PMC free article] [PubMed] [Google Scholar] 161.Olszak T., An D., Zeissig S., Vera M.P., Richter J., Franke A., Glickman J.N., Siebert R., Baron R.M., Kasper D.L

Endocrinology 156 (9), 31223136 (2015)

For the underlying logic of why this matters in middle age, see our overview of anti-aging in your 40s

Yet, overproduction of reactive oxygen species (ROS), induced by environmental toxins, inflammation, or mitochondrial dysfunction, overwhelms the cellular antioxidant defense system, resulting in oxidative stress [27]

Surgery is a one-time expense but requires lifelong lifestyle adjustments

Loss of the nf2 gene produces a devastating regeneration defect in genetically engineered mice, resulting in a continuous wound response signaling