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J Obes Metab Syndr 32(1):2545 Tian S, Zhou S, Wu W, lin Y, Wang T, Sun H, et al (2025) GLP-1 Receptor agonists alleviate diabetic kidney injury via -klotho-mediated ferroptosis inhibition

Notably, there is a strong correlation between elevated intramyocellular lipid (IMCL) levels and reduced insulin sensitivity, highlighting IMCL accumulation as a key contributor to insulin resistance [206, 207]

Obesity is associated with worse outcomes in hospitalized patients with inflammatory bowel diseases: A nationwide analysis

They are very similar to the GLP-1 hormone in your body and target the same receptors, mimicking its effects

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Dose escalation is gradual to minimise gastrointestinal side effects such as nausea and vomiting