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doi:10.36849/JDD.6550 Samantha Ouellette BA, Giulia Frias BA, Radhika Shah MD PharmD, Mahin Alamgir MD, Cindy Wassef MD Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Somerset, NJ Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic agents that work by inducing insulin secretion and inhibiting release of glucagon in a glucose-dependent manner
Not recommended during pregnancy or lactation without medical advice
However, potassium sorbate is generally recognized as safe (GRAS) by regulatory authorities
Current therapeutic strategies for T2DM management prioritize metformin as the first-line pharmacological intervention, primarily through its dual mechanisms of suppressing hepatic gluconeogenesis and enhancing peripheral glucose utilization in skeletal muscle tissue 3,4
It does not establish an authorised indication, effective dose, long-term safety profile or meaningful patient benefit
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