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A large international study suggests that a subset of people with Type 2 diabetes carry genetic variants that blunt the effectiveness of widely used GLP-1based drugs, despite unexpectedly elevated levels of the hormone in their bodies
However, during clinical trials, researchers observed that these medications also led to significant weight loss in many participants, prompting further studies specifically targeting populations with obesity
7 In line with JMs priorities for care, this approach could reduce his risk for a future cardiovascular event, promote weight loss, and would be considered to have a low risk for contributing to hypoglycemic events
Allergic reactions to medication and food can cause neck lumps
This article explains the evidence around stopping GLP-1 therapy, what to expect when treatment ends, and how to discontinue safely under medical supervision in line with UK clinical guidance