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The most common adverse events (AEs) associated with use of SGLT2 inhibitors are considered related to the pharmacologically elevated level of glucose in the urine, increasing the risk of osmotic diuresis, genital mycotic infections, and less frequently, urinary tract infections (UTIs)

Semaglutide activates GLP-1 receptors in the gut, brain, and pancreas

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The exploration of new therapeutic targets, the development of predictive tools for treatment response, and the refinement of guidelines for combined therapy will be critical in enhancing care for patients with coexisting conditions

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10.1677/JME-09-0160 99 Garca-SantamarinaS.BoronatS.HidalgoE