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Besides autophagy, FAs can also be derived from the decomposition of excess lipids by neutral lipases, such as adipose triglyceride lipase and hormone-sensitive lipase, which help cover energy shortages under metabolic stress (86, 87) ( Figure 1 )

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On the other hand, a meta-analysis of randomized clinical trials and a systematic review of observational studies reported no increased risk of pancreatitis or pancreatic cancer in patients treated with GLP1RA [86,87]

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