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Adjunct Strategy: When standard therapies are stable but symptoms remain refractory, LDN (naltrexone) is introduced as a structured, monitored adjunct add-on

doi: 10.1038/sj.onc.1209974 73 LeeYSLeeDHChoudryHABartlettDLLeeYJ

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This matters because even minor sequence variations can alter receptor binding affinity and downstream signaling effects

An example of such an enzyme is superoxide dismutase (Cu, Zn-SOD

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