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Non-clinical PK/PD modeling facilitates the selection of doses for the FIH trial

Dihexa solutions were prepared by suspending dry stock dihexa in DMSO at 3 rag/niL and subsequent serial dilutions in 50% DMSO or HPLC grade water for the final the proteins present in the plasma samples were precipitated using three volumes of ice-cold acetonitrile

Here, we investigated the effects of maternal L-Carnitine supplementation on brain markers of oxidative stress, autophagy, mitophagy and mitochondrial energy producing oxidative phosphorylation (OXPHOS) complexes in SE offspring

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10.1155/2012/428010 Oxid

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