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It act outside the cell to reduce cystine to cysteine which can be transported into the cell 10 times faster than cystine and further used in the biosynthesis of GSH

Academic Press, pp 302310 Callahan HL, Crouch RK, James ER (1988) Helminth antioxidant enzymes: a protective mechanism against host oxidants

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The condition can cause hemorrhages in the eye, retinal detachment, glaucoma and blindness

Putting myself in Pfizers shoes, the real kicker, beyond the potential for a better product profile, is how the potency and dosing of Metseras molecules lower API requirements and impact COGs

Back Holst, JJ, Smidt Gasberg, L