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The compound significantly enhances the effectiveness of gemcitabine in intrahepatic cholangiocarcinoma by inhibiting HDAC activity and restoring expression of pro-apoptotic genes (81)

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The evidence available to support the beneficial effect in maintenance of gastrointestinal mucosal homeostasis is summarized in Table 1

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(10) NAC zwiksza poziom glutationu i wydua ywotno komrek - badanie in vitro wykazao, e wzrost poziomu GSH w komrkach po traktowaniu ich N-acetylo-l-cystein wpywa na wyduenie ich ywotnoci w porwnaniu do komrek w hodowli kontrolnej, z obnionym poziomem GSH