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659 Nanotechnology-based strategies, such as lipid and polymeric nanoparticles, have been widely investigated for their potential application in improving drug delivery to enhance action to the target area to mitigate diabetic neuropathic pain

Key results from Calocurb's fourth human clinical study include the following: Calocurb is clinically shown to improve body composition by reducing body fat without losing muscle mass Average weight loss of 8.3 lbs (3.77 kg) after six months, compared to 0.88 lbs (0.4 kg) with the placebo group Over 6.5x greater reduction in body fat vs placebo Average body fat loss of 9.9 lbs (4.49 kg) vs 1.5 lbs (0.68 kg) after six months of consistent use of Calocurb vs placebo 3.5x greater reduction in visceral fat vs placebo Average visceral fat loss of 5 in2 (32.5 cm2) vs 1.4 in2 (9.1 cm2) lost after six months of consistent use of Calocurb vs placebo For over a decade, Calocurb has undertaken ground-breaking clinical research into Amarasate to continue bringing natural weight management solutions to those interested in GLP-1 and weight loss options.

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