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The role of GLP-1 in the nervous system largely, but not exclusively, complements peripheral actions of this peptide and encompasses suppression of food and water intake and the reduction of appetite and food reward

Published work treats the addition of glucagon-receptor agonism as its principal pharmacological distinction from dual GIP/GLP-1 agonists such as Tirzepatide

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Exenatide immediate-release requires taking oral contraceptives at least 1 hour before administration