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Methionine can be converted into S-adenosylmethionine (SAM) by SAM synthetase

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Although treatments are usually effective for managing thyroid function, individual genetic, environmental, or lifestyle factors that affect disease outcome and/or response to therapy are generally ignored

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Trapp S, Brierley DI (2022) Brain GLP-1 and the regulation of food intake: GLP-1 action in the brain and its implications for GLP-1 receptor agonists in obesity treatment