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There is no doubt about the malignant and metastatic potential of melanoma tumorigenesis, and the heterogeneity and plasticity of their cells

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Effects of ionic strength and chloride ion on activities of the glucose-6-phosphatase system: regulation of the biosynthetic activity of glucose-6-phosphatase by chloride ion inhibition/deinhibition

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However, this pioneering approach was futile due to the relatively thick mucosal barrier and continuous flow of saliva