Market stakeholders are aligning R&D objectives with long-term disease burden projections
The following data were extracted from each article: Organism Origin of sample (including whether the study was in vivo or in vitro) Sample size Study design Resistance status of study organism (suspected resistance, confirmed resistance, confirmed reduced tolerance, susceptible) Mechanism of resistance (target-site/metabolic/efflux pump-related, gene location, corresponding mutation, or metabolite implicated in the resistance mechanism) Intensity of resistance The data were summarised in a table, and the methodology, setting, and results of each study were synthesised narratively
Stress and obesity
Furthermore, combining network pharmacology with metabolomics allows for more robust verification of the multi-target mechanisms underlying Chinese medicines antidepressant properties, thus strengthening the scientific foundation for its clinical application [548]
Pancharuniti et al, 1994) and of cerebrovascular disease (Giles et al, 1995)
Supporting Peptides Additional sequences may include peptides studied for antioxidant properties and cellular communication support
