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The clearance of ibuprofen is mediated through oxidative metabolism by multiple cytochrome P450 (CYP) enzymes (CYP2C9, CYP2C8) to inactive primary metabolites including 3-hydroxy-ibuprofen, carboxy ibuprofen and 2-hydroxy-ibuprofen 5,6
Aquilano K, Baldelli S, Ciriolo MR
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An elemental diet has also been shown to decrease inflammatory parameters in IBD intestinal tissue
