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Limited evidence exists that semaglutide directly causes b12 deficiency in most patients

A new trend is sweeping the internet, with reports of some people taking the drug in very small doses for longevity even though health experts warn the effect is yet to be proven in humans

Aoyama E, Watari I, Podyma-Inoue KA, Yanagishita M, Ono T (2014) Expression of glucagon-like peptide-1 receptor and glucose-dependent insulinotropic polypeptide receptor is regulated by the glucose concentration in mouse osteoblastic MC3T3-E1 cells

Actual schedules vary by provider

Where a status quo approach breaks, and how centralized tracking helps