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Mechanistically, calcitriol upregulates key lipid-synthesizing enzymesincluding fatty acid synthase (FAS), 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA reductase), and serine palmitoyltransferase (SPT)and promotes lamellar body maturation and secretion, thereby enhancing stratum corneum structural cohesion [234,235,236]

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Guan S, Xu J, Guo Y, Ge D, Liu T, Ma X, Cui Z

We established an in vitro model by treating HK-2 cells with CaOx

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Compounds such as 2"--L-rhamnopyranosyl-hyperin, quercitrin 3-O--D-neohesperidoside, miquelianin, quercetin 3-O--D-galacturonopyranoside, isoquercitrin, hyperin, and hyperin 6"-O-gallate, separated from the leaves, demonstrated radical-scavenging properties (633)