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The Critical Birth Control Conversation This cannot be overstated: Use effective contraception while taking GLP-1 medications

What happens if I want to stop treatment

In a clinical trial in pediatric patients aged 12 years and older with normal baseline heart rate, more patients treated with WEGOVY compared to placebo had maximum changes in heart rate of 20 bpm or more (54% versus 39%)

Convenient once-weekly injection : Like other medication in this class, retatrutide is a once-a-week injection that is easier to adhere to than daily treatments

These improvements were typically accompanied by increases in sex hormone-binding globulin (SHBG) due to improved insulin sensitivity, which affects the interpretation of total versus free testosterone measurements

But when properly managed, the synergy between fat loss and hormonal optimization produces body composition changes that exceed what either intervention achieves alone