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Dass S, Cochlin LE, Suttie JJ, Holloway CJ, Rider OJ, Carden L, Tyler DJ, Karamitsos TD, Clarke K, Neubauer S, Watkins H (2015) Exacerbation of cardiac energetic impairment during exercise in hypertrophic cardiomyopathy: a potential mechanism for diastolic dysfunction

Another key point: stopping therapy leads to regain in most people, which argues for getting to and staying at an effective maintenance dose rather than hovering at subtherapeutic levels

Muscle craves protein and without resistance exercise and appropriate protein energy, the body will cannibalize muscle for energy

The STEP-1 trial, one of the landmark studies for semaglutide 2.4mg, showed that participants lost approximately 9.7% of their lean mass alongside a 19.3% reduction in fat mass

VCTE, vibration-controlled transient elastography

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