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doi: 10.1158/0008-5472.CAN-07-6705 56 SawanoAIwaiSSakuraiYItoMShitaraKNakahataTet al

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Drug Discovery Today 7 , 57 (2002)

Disruptions to core clock gene expression, which can occur from exposure to light at night or repeated phase shifts resulting from social jet lag can result in significant disruption in the tissue recovery process, which in the context stroke, could result in increased ischemic damage and could be detrimental to patient outcome

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