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Shaking creates mechanical stress that can denature the semaglutide molecule, breaking the structural bonds that give it biological activity

'Akin to a vaccine' against effects of a pathogen "It is rare for a cardio-metabolic drug to modify non-cardiovascular outcomes," lead author Benjamin Scirica, MD, MPH, director of quality initiatives at Brigham and Women's Hospital's Cardiovascular Division, said in a Brigham news release

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Our published research found an average weight loss of 19.1% at 12 months in active subscribers on a GLP-1-supported programme, with 77.7% losing at least 10% of their body weight