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Together, these effects support meaningful weight reduction alongside diet and activity

In some rare cases, statins may cause muscle damage, thinking issues, or atypical liver enzyme test results, although significant liver damage is uncommon

The Human Gene Mutation Database (HGMD) contains 43 different GSS variants that have been reported as of January 2023, with missense variants showing predominance (55.8%), followed by splice variants (21.0%), small insertions/deletions (11.5%), large insertions/deletions (7.0%), and nonsense variants (4.7%)

In fact, weve been talking about the bigger picture around semaglutide for months on the podcast and in our functional medicine telehealth clinic

Journal of Weight Management , 29(4), 300-310

The PDCs currently under clinical/preclinical trials are summarized in Table 6