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The biggest differences are how they are administered, how often you need to take them, and how effective they are

Nutr Metab (Lond) 7 , 30 (2010)

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Gastrointestinal side effects: Nausea and vomiting, bloating, and bowel changes GI side effects are the most commonly reported GLP-1 side effects, especially when first starting or increasing your dose

Hexarelin also binds with growth hormone secretagogue receptor (GHS-R1a) (2) similar to ghrelin to initiate a phospholipid-dependent protein kinase (PKC) signaling pathway (1)