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The risk of precipitating the serotonin syndrome is increased if serotonergic drugs with different mechanisms of action are ingested, even weeks apart [182,183,184]

Nicolson R, Lenane M, Hamburger SD, Fernandez T, Bedwell J, Rapoport JL (2000)

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Various factors can induce changes in their chemical composition, morphology, and structure, thus altering their function

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