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Dopaminergic dysfunctions in schizophrenia Since the dopaminergic system is an important player in multiple functions of human body as reviewed above, it is not surprising that malfunctions of dopaminergic signaling have been implicated in the pathogenesis of various human disorders including PD, HD, ADHD, schizophrenia, and addiction [11]

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DOI: 10.1016/j.smrv.2019.101234

By 2050, this number is projected to more than double to 48.3 million