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After the printed date, the company and the regulator stop guaranteeing full potency not because the tablet suddenly becomes dangerous that day, but because they havent committed to data beyond it

(Frontiers in Pharmacology, 2022) reports a half-life under 30 minutes after IM or IV administration in rodent and dog models, which is why split-dose schedules appear in the literature

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Proper IV technique (choosing the right vein and catheter size, and not placing IVs near areas of flexion for too long) helps prevent these