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Medications with narrow therapeutic windows may need dose adjustments

One possible mechanism is the elevation of the lipid-responsive nuclear receptor LXR, together with its target genes NPC1 and NPC2 (Figure 3)

skin lightening creams and lasers may be associated with various adverse side effects such as skin irritation, redness, hypopigmentation or rebound hyperpigmentation

Mild cognitive impairment: An epidemiological perspective

When AOD-9604 activates these receptors in fat tissue, it triggers localized lipolytic responses without sending signals to the brains feeding centers

In severe cases, intravenous administration may be considered, but only under medical supervision