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Patients with metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and insulin resistance may experience improvements in hepatic steatosis and liver enzyme elevations, though this represents an off-label use with evolving evidence

Reviewers report polarized outcomes: some patients see modest results, many see no measurable response and request a switch to injectables

The B12 addition is a bonus that Wegovy does not include

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This off-label promotion meant millions of otherwise healthy individuals were prescribed Ozempic for weight management without understanding they were taking a powerful medication with serious adverse effects

This was replicated for others, but not in all studies published that look at this