Sorli C, Harashima SI, Tsoukas GM, Unger J, Karsbl JD, Hansen T, et al
Talk with your primary care provider or OB about whether other medications (such as orlistat, a lipase inhibitor with a longer safety track record in pregnancy) might bridge your weight management during the pre-conception and early pregnancy window
The most significant contraindication for this combination injection is a known hypersensitivity or allergy to tirzepatide, niacinamide, or any component of the formulation
Constipation at higher doses Constipation becomes more common as your dose increases, particularly above 1.0 mg
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Switching is possible but must be managed carefully by a healthcare professional