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318,319 GIPR has been detected in adipose tissue and genetic ablation of GIPR in mice has clearly shown the importance that GIP has on fat uptake: GIPR-deficient mice did not develop weight gain and adiposity to the same degree as control mice even though they were on the same high-fat diets

The clinical evidence linking mycotoxin exposure to ME/CFS has grown significantly over the past decade, largely driven by functional medicine researchers seeking root causes for the disease

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And while results can be impressive in the short term, the long-term picture is more complex: in one clinical study, participants regained two-thirds of their lost weight within a year of stopping treatment

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Taken together, the LAG-1 AID time course results supports the findings from the initial genome-wide analysis that lst-1 and sygl-1 are likely the only two mRNA transcriptional targets of GLP-1 signaling in the germline