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Zepbound (tirzepatide) is a prescription medication approved by the FDA in November 2023 for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity

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In January 2025, the FDA approved Semaglutide (O) for a third indication: to reduce the risk of worsening kidney disease, kidney failure, and cardiovascular disease-related death in adults with type 2 diabetes and chronic kidney disease