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Menopausal women face unique challenges due to fluctuating hormones

Two definitions (one more sensitive, the other more specific) were used to identify cases of NAION

A 2015 paper shows that the influenza A virus directly activates mast cells, causing the release of cytokines and contributing to the excessive inflammatory response in the lungs.[ref] Animal studies show that this pattern of mast cell activation and excessive response holds true for several flu strains

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However it is not a cognitive enhancer for those with normal B vitamin levels