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Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

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IV glutathione is used for liver disorders, supports kidney function under oxidative load, and is recommended for patients with conditions like hepatitis where detox capacity is impaired

63 Additionally, ample GSH improves cell viability, whereas its depletion drastically increases susceptibility to ROS-inducing antibiotics