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Another study suggested that artesunate ameliorated LPS-mediated release of apoptotic proteins NLRP1, CASP-3, ASC, and CASP-1 in NR8383 cells by regulating SIRT1 expression in vivo (Liu Z

PMID 16955738

In the case of suspected cobalt hypersensitivity, an intradermal test dose should be administered because anaphylactic shock and death have followed parenteral administration of methylcobalamin

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