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3.4 Other regulatory mechanisms of ferroptosis There are several classical signaling pathways, which either synergize with ferroptosis or act as upstream regulatory signals that influence cancer cell survival and proliferation, including PI3K/Akt, Wnt/-catenin, p53, ACSL4, Caspase-1-dependent pyroptosis, and AMP-activated protein kinase (AMPK)/ Beclin1 (BECN1) signal pathways

doi: 10.1038/s41581-020-0278-5 227 LiLChenHWangMChenFGaoJSunSet al

Prog Neuropsychopharmacol Biol Psychiatry 2002

As people age, the production of hyaluronic acid decreases, leading to drier and less elastic skin

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