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10.3390/molecules21070886 2 AlharbiI.AlharbiH.AlmogbelY.AlalwanA.AlhowailA

doi:10.1186/s12933-021-01412-5 Coskun T, Sloop KW, Loghin C, et al

Potential Applications of Melanotan I Laboratory studies and in vitro testing have demonstrated that Melanotan I peptide could hold the following benefits: Sunless Tanning: Melanotan I enhances skin pigmentation by stimulating melanin production in melanocytes

Other components (excipients): sodium hydrogen phosphate heptahydrate, benzyl alcohol, glycerol, phenol crystalline, sodium chloride, 10 % diluted hydrochloric acid and/or 10 % sodium hydroxide solution (for pH adjustment), water for injection

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If the abovementioned is occurring, it could mean that IGF-1 administration could also lower glucose levels by suppressing hepatic gluconeogenesis, as well as improving insulin signalling in this organ, leading to IGFBP-1 suppression and overall improvement of the IGF-1/GH/insulin axis