soul trial oral semaglutide cardiovascular outcomes 2024 2025 SELECT soul trial oral semaglutide cardiovascular

Boewe AS, Wrublewsky S, Hoppstdter J, Gtz C, Kiemer AK, Menger MD, et al

STEP 5, the longest trial at 104 weeks, showed that weight loss was sustained over two years of continuous treatment

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With correct physical activity, diet and lifestyle modifications, semaglutide users saw significant improvements in weight-related conditions like high blood pressure, high cholesterol and heart disease