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In at least one case (the photosynthetic alga ), both - type and metazoan-type TrxRs are found in the same genome (Novoselov and Gladyshev, 2003)

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Correction in J

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(2) loss of enzymatic activity leads to a shift to a cardiovascular pro-damaging axis of the RAAS involving higher levels of Ang II followed by reduced production of Ang(17) 30, 31

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