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Prescribing information for approved GLP-1 medications does not list colorectal cancer as a known adverse effect, though the FDA requires ongoing post-marketing surveillance for all novel therapeutic agents

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However, analysis of carnosine in complex samples by liquid chromatography can suffer stationary phase damage from matrix species and often requires the use of precolumn, large quantities of organic solvents, and bulky instrumentation [46]

Nguyen et al., 2022)