Our experience shows that understanding these mechanisms can empower patients to manage them effectively
[5] Wee, L.E
doi: 10.1007/s10495-021-01687-9 192 PereiraJFJordanPMatosP
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It is possible that the latter group might find a reduction in the efficacy of their HRT when using tirzepatide (for the same pharmacokinetic reasons discussed regarding contraception), but the likelihood and magnitude of this is unknown

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